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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:
1. A study is conducted comparing two antibiotics for the treatment of UTIs. The results after 7 days of therapy demonstrated that Drug A was superior to Drug B in eradicating bacteria from the urine and eliminating signs and symptoms of infections. The investigators concluded that Drug A was significantly superior to Drug B (p<0.05). In subsequent studies, however, the two drugs were equivalent in efficacy.
Which one of the following types of error apparently occurred in the first study?
A) Beta error
B) Type ||
C) Regression to the mean
D) Type |
2. A 55 year old woman being treated for hypothyroidism with levothyroxine 125 mcg daily is currently euthyroid. She now has menopausal symptoms and is receiving conjugated estrogens.
What effect is this most likely to have on her thyroid function tests?
A) Decreased total T4
B) Decreased free T4
C) No changes in reverse triiodothyronine uptake
D) No changes in TSH
3. A study compared treatment with cinacalcet versus treatment with placebo in subjects with known hyperparathyroidism. The primary outcome of the study was the proportion of study subjects with a mean intact parathyroid hormone level < 250 pg/mL. Among the cinacalcet group (n = 371), 43% of subjects achieved the primary outcome; among the placebo group (n =
370), 5% achieved the primary outcome (p<0.05).
Which of the following is the number needed to treat (NNT)?
A) 14
B) 3
C) 8
D) 1
4. A 66-year-old man with a history of chronic bronchitis is seen in October for treatment of an acute exacerbation. He received the pneumococcal vaccine 3 years ago and an influenza vaccine this past March. Which of the following should the pharmacotherapy specialist recommend?
A) Neither Vaccine
B) Oseltamivir With influenza Vaccine
C) Influenza Vaccine
D) Both Vaccines
5. The prophylaxis of postsurgical deep vein thrombosis was reviewed in an article published 5 years ago. A researcher wishes to identify any studies since then that have used this article as a reference. What is the most appropriate database for this search?
A) The Cochrane Collaboration
B) Science Citation Index
C) International Pharmaceutical Abstracts
D) MEDLINE
Solutions:
| Question # 1 Answer: D | Question # 2 Answer: A | Question # 3 Answer: B | Question # 4 Answer: A | Question # 5 Answer: D |


